An Important Cause of Morbidity in Preterm Babies; Necrotizing enterocolitis: A Two-year Evaluation

Abstract

INTRODUCTION: In our study, we aimed to evaluate the risk factors that influenced development of necrotizing enterocolitis (NEC) in preterm babies born at a gestational age below 32 weeks who were being followed up in our neonatal intensive care unit. METHODS: Babies who were born at a gestational age below 32 weeks in our hospital were evaluated in terms of perinatal and postnatal risk factors for the development of NEC. Demographic and clinical characteristics of babies were recorded. IBM SPSS Statistics 21,0 program was used for statistical evaluation. RESULTS: Eighty-five preterm babies were included in our study. The birth weight and gestational week of the subjects were found to be 1190(380-1650) grams and 29(21-31) weeks, respectively. The birth weight and gestational week were found to be significantly lower in the subjects who developed necrotizing enterocolitis compared to the subjects who did not develop NEC(p: 0,005; p: 0,035). The incidence of NEC was found to be 11,7% (n: 10) in preterm babies. Doppler ultrasonography revealed abnormal findings in five of the subjects who developed NEC and in 12 of the subjects who did not develop NEC; this difference was statistically significant (p: 0,002). Surgical laparotomy were performed in five subjects. The mean birth weight and gestational week of these subjects were found to be significantly lower compared to the ones who did not require surgery(p: 0,015; p: 0,042). DISCUSSION AND CONCLUSION: Especially premature babies with lower gestational week and very low birth weight, whom cannot tolerate minimal enteral feeding, have abnormal Doppler ultrasound findings or blood transfusion history should be monitored more carefully.

Keywords

• necrotizing enterocolitis
• preterm
• risk factors
• incidence