Revista de la Facultad de Medicina (Jan 1996)
Antritis nodular en adultos: relación con el Helicobacter pylori
Abstract
Helicobacter pylori is currently the commonest cause of chronic gastritis. In this work we investigated the association of endoscopic antral aspect in cobblestone and the gastric infection by H pylori. 60 patientes were studied, all of them had a non-ulcer dyspepsia; mean age was 27.0 +/- 7.0 years and patients were predominantly females (n=41). The fast urease test was always positive and the histophatological findings were: an important chronic Iymphocitic and plasmocitic infiltrate of tbe gastric mucosa; activity was present in 72% of the cases and lymphoid follicles were observed in 88%. H pylori was demonstrated in all patients and colonization was severe in 75% of the cases. The possibility that this exagerated immunitary response in youg people is due to a chronic infection by H pylori, is proposed. In addition, if this Iymphocitic predominant infiltrate develops in some cases to gastric MALT lymphoma should be investigated.