Wellcome Open Research (May 2021)
The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769 [version 1; peer review: 2 approved]
- Kerstin Howe,
- Melinda Dwinell,
- Mary Shimoyama,
- Craig Corton,
- Emma Betteridge,
- Alexander Dove,
- Michael A. Quail,
- Michelle Smith,
- Laura Saba,
- Robert W. Williams,
- Hao Chen,
- Anne E. Kwitek,
- Shane A. McCarthy,
- Marcela Uliano-Silva,
- William Chow,
- Alan Tracey,
- James Torrance,
- Ying Sims,
- Richard Challis,
- Jonathan Threlfall,
- Mark Blaxter
Affiliations
- Kerstin Howe
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Melinda Dwinell
- Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA
- Mary Shimoyama
- Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA
- Craig Corton
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Emma Betteridge
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Alexander Dove
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Michael A. Quail
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Michelle Smith
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Laura Saba
- Skaggs School of Pharmacy and Pharmaceutical Sciences,, University of Colorado Anschutz Medical Center, Aurora, Colorado, 80045, USA
- Robert W. Williams
- Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee, 38103, USA
- Hao Chen
- Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, Memphis, Tennessee, 38103, USA
- Anne E. Kwitek
- Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA
- Shane A. McCarthy
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Marcela Uliano-Silva
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- William Chow
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Alan Tracey
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- James Torrance
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Ying Sims
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Richard Challis
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Jonathan Threlfall
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- Mark Blaxter
- Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
- DOI
- https://doi.org/10.12688/wellcomeopenres.16854.1
- Journal volume & issue
-
Vol. 6
Abstract
We present a genome assembly from an individual male Rattus norvegicus (the Norway rat; Chordata; Mammalia; Rodentia; Muridae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20 chromosomal pseudomolecules, with both X and Y sex chromosomes assembled. This genome assembly, mRatBN7.2, represents the new reference genome for R. norvegicus and has been adopted by the Genome Reference Consortium.
