Heliyon (Jun 2023)

Bone marrow metastasis of testicular germ cell tumour: A rare case

  • Harshita Dubey,
  • Garima Jain,
  • Chandan Kumar,
  • Amar Ranjan,
  • Atul Batra,
  • Santosh Kumar Chellapuram,
  • Swati Gupta,
  • Harsh Goel,
  • Anil Sharma,
  • Pranay Tanwar

Journal volume & issue
Vol. 9, no. 6
p. e16703

Abstract

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Germ cell tumour (GCT) is the most common testicular tumour that commonly presents as a painless mass. Bone marrow metastasis in cases of testicular GCT is rare; only few case reports are available till date in the literature. Here an adult male presented with an intra-abdominal mass in right iliac fossa with inguinal lymphadenopathy with a deranged kidney function test. Bone marrow (BM) aspirate smear revealed metastatic tumour cells, but BM-biopsy was unremarkable. High serum Beta - HCG (38286 mIU/L) pointed towards germ cell lesion. Lymph node biopsy along with immunomarkers confirmed metastatic foci from germ cell tumor and managed as per standard protocol. Rarely BM aspirate is seen positive for malignancy, while biopsy turns out to be negative. Secondly, BM metastasis of GCT should be considered while dealing with cases like this. Informed consent: This is certified that the informed consent has been obtained from the patient.

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