Nature Communications (Aug 2020)

Predicting distant metastasis and chemotherapy benefit in locally advanced rectal cancer

  • Zhenyu Liu,
  • Xiaochun Meng,
  • Hongmei Zhang,
  • Zhenhui Li,
  • Jiangang Liu,
  • Kai Sun,
  • Yankai Meng,
  • Weixing Dai,
  • Peiyi Xie,
  • Yingying Ding,
  • Meiyun Wang,
  • Guoxiang Cai,
  • Jie Tian

DOI
https://doi.org/10.1038/s41467-020-18162-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal cancer. Here, the authors developed and validated a radiomic signature (RS) for prediction of DM within a multicenter dataset, and suggest that it may help with stratification of patients who might benefit from adjuvant chemotherapy for DM.