Nature Communications (Nov 2017)

Label-free nanoscale optical metrology on myelinated axons in vivo

  • Junhwan Kwon,
  • Moonseok Kim,
  • Hyejin Park,
  • Bok-Man Kang,
  • Yongjae Jo,
  • Jae-Hwan Kim,
  • Oliver James,
  • Seok-Hyun Yun,
  • Seong-Gi Kim,
  • Minah Suh,
  • Myunghwan Choi

DOI
https://doi.org/10.1038/s41467-017-01979-2
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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Spectral reflectance has been used to achieve label-free, in vivo imaging of myelin, a membranous sheath that allows faster electrical conduction along neuronal axons. Here the authors extend this technique to measure nanoscale features, including changes following traumatic brain injury.