Indian Journal of Pathology and Microbiology (Jan 2018)

Keratomycosis due to Purpureocillium lilacinum: A case report from Sub-Himalayan region of Uttarakhand

  • Deepak Juyal,
  • Shekhar Pal,
  • Munesh Sharma,
  • Vikrant Negi,
  • Shamanth Adekhandi,
  • Manoj Tyagi

DOI
https://doi.org/10.4103/ijpm.ijpm_404_17
Journal volume & issue
Vol. 61, no. 4
pp. 607 – 609

Abstract

Read online

The fungus Purpureocillium lilacinum previously known as Paceliomyces lilacinus is an emerging pathogen that can cause severe human infections including devastating oculomycosis. Treatment with traditional antifungals often fails, and the organism shows variable susceptibility to novel triazoles. We hereby report a case of keratomycosis caused by Pur. lilacinum in an immunocompetent male patient following trauma. The patient was successfully treated with voriconazole. The drug shows good activity against Pur. lilacinum and could be a promising therapeutic alternative to treat infections caused by this fungus, which generally shows resistance to conventional antifungal agents including novel triazoles.

Keywords