Nature Communications (Mar 2019)

Characterization of the hemodynamic response function in white matter tracts for event-related fMRI

  • Muwei Li,
  • Allen T. Newton,
  • Adam W. Anderson,
  • Zhaohua Ding,
  • John C. Gore

DOI
https://doi.org/10.1038/s41467-019-09076-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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The hemodynamic response function (HRF) describes how changes in brain activity manifest as a transient signal (BOLD) that is detected by fMRI imaging. Here, the authors show that the HRF in white matter shows reduced magnitudes, delayed onsets, and prolonged initial dips compared to the grey matter HRF.