Prevalencia de anticuerpos contra dengue y leptospira en la población de Jáltipan, Veracruz Prevalence of dengue and leptospira antibodies in the state of Veracruz, Mexico

Abstract

OBJETIVO: Conocer la prevalencia de anticuerpos contra dengue y leptospira en Jáltipan, Veracruz, México MATERIAL Y MÉTODOS: Estudio transversal en 500 habitantes de Jáltipan, Veracruz, mediante un muestreo por hogares, aplicación de cuestionario y toma de muestras sanguíneas. Se buscaron anticuerpos IgG y se evaluaron factores asociados a sus seroprevalencias mediante regresión logística RESULTADOS: La seroprevalencia global para denguevirus fue 79.6% (IC95% 76-81); los principales factores vinculados con la infección fueron la edad (pOBJECTIVE: To discover the prevalence of antibodies against denguevirus and leptospira. MATERIAL AND METHODS: A cross-sectional study was carried out in 500 inhabitants of Veracruz, Mexico through household sampling, administration of a questionnaire and collection of blood samples. The presence of IgG antibodies was determined and factors associated with seroprevalence were evaluated using a logistic regression model. RESULTS: Total denguevirus seroprevalence was 79.6% (IC95% 76-81). The main factors associated with infection were age and residence in neighborhoods with higher vectorial indices (RMP=2.94, IC95% 1.46-6.1). Overall seroprevalence against leptospira was 4% (IC95% 2-6). Prevalence was higher in the 25 to 44 years age group (35%, IC95% 15-59). Seroprevalence in individuals who referred to living with dogs, pigs, cows and rats was 25% (IC95% 0.63-80). Eighty-five percent of individuals who were leptospira positive were also dengue positive. CONCLUSIONS: The prevalence of denguevirus antibodies suggests the risk of serious dengue hemorrhagic outbreaks. Although leptospirosis prevalence was low, the coexistence of both agents was confirmed.

Keywords

• dengue
• leptospira
• anticuerpos
• prevalencia
• México
• dengue
• leptospira
• antibodies
• prevalence
• Mexico