Sarcoma (Jan 1999)

Oncogenic Osteomalacia as a Harbinger of Recurrent Osteosarcoma

  • Elizabeth B. Lamont,
  • Melissa K. Cavaghan,
  • Bruce E. Brockstein

DOI
https://doi.org/10.1080/13577149977712
Journal volume & issue
Vol. 3, no. 2
pp. 95 – 99

Abstract

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Discussion. Oncogenic osteomalacia is a rare paraneoplastic syndrome of skeletal demineralization from renal phosphate loss. Patients with this disorder have the characteristic clinical, laboratory, and radiographic findings of hyperphosphaturic osteomalacia. Although the pathophysiology has not yet been clearly delineated, a humoral factor produced by the tumor is suspected to be the cause.