Plasmonic silver nanoshells for drug and metabolite detection

Lin Huang; Jingjing Wan; Xiang Wei; Yu Liu; Jingyi Huang; Xuming Sun; Ru Zhang; Deepanjali D. Gurav; Vadanasundari Vedarethinam; Yan Li; Ruoping Chen; Kun Qian

doi:10.1038/s41467-017-00220-4

Nature Communications (Aug 2017)

Plasmonic silver nanoshells for drug and metabolite detection

Lin Huang,
Jingjing Wan,
Xiang Wei,
Yu Liu,
Jingyi Huang,
Xuming Sun,
Ru Zhang,
Deepanjali D. Gurav,
Vadanasundari Vedarethinam,
Yan Li,
Ruoping Chen,
Kun Qian

Affiliations

Lin Huang: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Jingjing Wan: Department of Chemistry, Shanghai University
Xiang Wei: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Yu Liu: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Jingyi Huang: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Xuming Sun: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Ru Zhang: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Deepanjali D. Gurav: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Vadanasundari Vedarethinam: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Yan Li: Institute of Biophysics Key Laboratory of Interdisciplinary Research, Chinese Academy of Sciences
Ruoping Chen: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University
Kun Qian: School of Biomedical Engineering, Children’s Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University

DOI: https://doi.org/10.1038/s41467-017-00220-4
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 10

Abstract

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Preparation of samples for diagnosis can affect the detection of biomarkers and metabolites. Here, the authors use a silver nanoparticle plasmonics approach for the detection of biomarkers in patients as well as investigate the distribution of drugs in serum and cerebral spinal fluid.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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