Monitoring of Pregnancy-Induced Hypertension Syndrome Combined with Ultrasound Monitoring in Early Pregnancy to Prevent Chronic Hypertension with Preeclampsia

Songyuan Xiao; Jinyu Liu; Bo Liu; Ling Yu; Yali Deng; Wen Zhang; Yanting Nie; Weisi Lai; Hongyu Liu; Yang Zhou; Li Yu; Ying Wen; Bo Zhou; Yanhong Zhong; Lingyi Xiao; Yiling Ding; Mei Peng

doi:10.31083/j.ceog5001016

Clinical and Experimental Obstetrics & Gynecology (Jan 2023)

Monitoring of Pregnancy-Induced Hypertension Syndrome Combined with Ultrasound Monitoring in Early Pregnancy to Prevent Chronic Hypertension with Preeclampsia

Songyuan Xiao,
Jinyu Liu,
Bo Liu,
Ling Yu,
Yali Deng,
Wen Zhang,
Yanting Nie,
Weisi Lai,
Hongyu Liu,
Yang Zhou,
Li Yu,
Ying Wen,
Bo Zhou,
Yanhong Zhong,
Lingyi Xiao,
Yiling Ding,
Mei Peng

Affiliations

Songyuan Xiao: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Jinyu Liu: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Bo Liu: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Ling Yu: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Yali Deng: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Wen Zhang: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Yanting Nie: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Weisi Lai: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Hongyu Liu: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Yang Zhou: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Li Yu: Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Ying Wen: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Bo Zhou: Department of Gynecology and Obstetrics, Ningxiang Hospital Affiliated to Hunan University of Traditional Chinese Medicine, 410600 Ningxiang, Hunan, China
Yanhong Zhong: Department of Gynecology and Obstetrics, Yuanjiang Maternal and Child Health Care Hospital, 413100 Yuanjiang, Hunan, China
Lingyi Xiao: Department of Gynecology and Obstetrics, Affiliated Hospital of Xiangnan University, 423000 Chenzhou, Hunan, China
Yiling Ding: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China
Mei Peng: Department of Gynecology and Obstetrics, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, China

DOI: https://doi.org/10.31083/j.ceog5001016
Journal volume & issue: Vol. 50, no. 1
p. 16

Abstract

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Background: This study explored the guiding value of monitoring pregnancy-induced hypertension syndrome (MP) for blood hypercoagulability in combination with ultrasound monitoring of uterine artery blood flow in early pregnancy and fetal growth and development in the second and third trimesters, with the goal of preventing chronic hypertension with preeclampsia (PE) and its clinical effects. Methods: The medical records of 189 pregnant patients with chronic hypertension between June 2016 and June 2021 were retrospectively analyzed; among them, 98 constituted the intervention group. The intervention group received MP screening for blood hypercoagulability in combination with ultrasound monitoring of uterine artery blood flow in early pregnancy and fetal growth and development in the second and third trimesters of pregnancy. Those with abnormalities were given timely symptomatic (low-molecular-weight heparin with or without aspirin) and supportive treatment. The remaining 91 patients who did not receive timely monitoring and intervention constituted the control group. Fetal outcomes and PE rates were compared between groups. Results: The PE incidence in the intervention group was significantly lower than that in the control group (p < 0.01), and the premature delivery of low-birth-weight neonates, fetal loss and neonatal asphyxia incidences were also significantly lower in the intervention group than the control group (p < 0.05). Conclusions: MP screening for blood hypercoagulability combined with ultrasound monitoring of uterine artery blood flow can effectively prevent PE occurrence in pregnant patients with chronic hypertension and significantly improve fetal outcomes. Additionally, MP screening is noninvasive and easy to use at a low cost.

Published in Clinical and Experimental Obstetrics & Gynecology

ISSN: 0390-6663 (Print); 2709-0094 (Online)
Publisher: IMR Press
Country of publisher: Hong Kong
LCC subjects: Medicine: Gynecology and obstetrics
Website: https://www.imrpress.com/journal/CEOG

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