Pediatric Neurology Briefs (Feb 2000)

Mechanism of the Ketogenic Diet

  • J Gordon Millichap

DOI
https://doi.org/10.15844/pedneurbriefs-14-2-4
Journal volume & issue
Vol. 14, no. 2
pp. 11 – 12

Abstract

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To elucidate the possible significance of ketone bodies in the mechanism of the ketogenic diet, researchers at Washington University School of Medicine, St Louis, MO, examined the effect of B-hydroxybutyrate and acetoacetate on excitatory and inhibitory synaptic transmission and spontaneous seizures in rat hippocampal slices and cultured hippocampal neurons.

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