Nature Communications (Oct 2019)
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
- Øyvind Helgeland,
- Marc Vaudel,
- Petur B. Juliusson,
- Oddgeir Lingaas Holmen,
- Julius Juodakis,
- Jonas Bacelis,
- Bo Jacobsson,
- Haakon Lindekleiv,
- Kristian Hveem,
- Rolv Terje Lie,
- Gun Peggy Knudsen,
- Camilla Stoltenberg,
- Per Magnus,
- Jørn V. Sagen,
- Anders Molven,
- Stefan Johansson,
- Pål Rasmus Njølstad
Affiliations
- Øyvind Helgeland
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- Marc Vaudel
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- Petur B. Juliusson
- Department of Clinical Science, University of Bergen
- Oddgeir Lingaas Holmen
- KG Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology
- Julius Juodakis
- Department of Gynecology and Obstetrics, Sahlgrenska Academy, University of Gothenburg
- Jonas Bacelis
- Department of Gynecology and Obstetrics, Sahlgrenska Academy, University of Gothenburg
- Bo Jacobsson
- Department of Genetics and Bioinformatics, Health Data and Digitalisation, Norwegian Institute of Public Health
- Haakon Lindekleiv
- Department of Community Medicine, UiT The Arctic University of Norway
- Kristian Hveem
- KG Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology
- Rolv Terje Lie
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- Gun Peggy Knudsen
- Department of Genetics and Bioinformatics, Health Data and Digitalisation, Norwegian Institute of Public Health
- Camilla Stoltenberg
- Department of Global Public Health and Primary Care, University of Bergen
- Per Magnus
- Centre for Fertility and Health, Norwegian Institute of Public Health
- Jørn V. Sagen
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- Anders Molven
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- Stefan Johansson
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- Pål Rasmus Njølstad
- KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
- DOI
- https://doi.org/10.1038/s41467-019-12308-0
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 10
Abstract
Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci.
