Adsorption of aluminum via surface modification: An effective way to reduce the aluminum contamination presented in H2O2 plasma sterilization
Ruixiang Hou,
Xiaomin Li,
Ang Gao,
Muhua Zhao,
Yang Zhang,
Ziang Xie,
Chuangnian Zhang,
Yan Zhang,
Cui Zheng,
Zifang Guo
Affiliations
Ruixiang Hou
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
Xiaomin Li
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
Ang Gao
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
Muhua Zhao
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
Yang Zhang
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
Ziang Xie
Beijing Key Laboratory for Magneto-Photoelectrical Composite and Interface Science, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, People’s Republic of China
Chuangnian Zhang
Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, People’s Republic of China
Yan Zhang
SINOPHARM Shenzhen Legend Medical MSSC, Shenzhen 518000, People’s Republic of China
Cui Zheng
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
Zifang Guo
SINOPEC (Beijing) Research Institute of Chemical Industry Co., Ltd., Beijing 100013, People’s Republic of China
In our recent work, it was first demonstrated that aluminum (Al) ions generated in the process of H2O2 plasma sterilization can penetrate the sterilization package and contaminate the surgical instrument inside. In this paper, it is first reported that Al ions can be adsorbed in plasma by sterilization package with surface modification, significantly reducing the contamination, up to 92%. The surface modification is carried out by introducing a functional layer on the surface of the sterilization package. The special chemical groups in the functional layer can combine with Al ions in two ways, ion exchange and chelation, preventing them from contaminating the surgical instrument in the sterilization package. Through the research on the diffusion coefficient of Al in Si sterilized using the modified sterilization packages, it is found that surface modification of sterilization packages has a great influence on the physical mechanism of Al contamination.