Right ventricular-pulmonary artery uncoupling in patients with atrial fibrillation on peritoneal dialysis
Tao Zhang,
Zijun Zhou,
Qianyi Zhou,
Jie Li,
Zhiwei Zhang,
Shili Cao,
Bo Yang,
Qingmiao Shao
Affiliations
Tao Zhang
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research, Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China
Zijun Zhou
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research, Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China
Qianyi Zhou
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research, Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China
Jie Li
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research, Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China
Zhiwei Zhang
Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University, Tianjin, People’s Republic of China
Shili Cao
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research, Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China
Bo Yang
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research, Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China
Qingmiao Shao
Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University, Tianjin, People’s Republic of China
Background Tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (PASP) as a noninvasively measured index of right ventricular-pulmonary artery uncoupling is associated with poor outcomes in heart failure patients. However, the relationship by which the TAPSE/PASP is linked to atrial fibrillation (AF) in peritoneal dialysis (PD) patients is not clear. We aimed to investigate the relationship between the TAPSE/PASP and AF in PD patients.Methods This study was divided into two parts. First, we included 329 PD patients. All the subjects provided detailed a medical history, laboratory analysis and transthoracic echocardiography on admission. We evaluated the differences in the TASPE/PASP ratios between the AF and non-AF groups. Second, a total of 121 patients were followed up to compare mortality between the AF and non-AF groups.Results Age, BNP, RDW, LA, and septal E/e’ were significantly higher, and TAPSE/PASP was significantly lower in patients with AF than in those without AF (p 0.715.Conclusions The results suggested that the TAPSE/PASP was lower in AF patients than in non-AF patients. The TAPSE/PASP may be a useful factor for predicting mortality in AF patients with PD, but large-scale prospective studies are needed for verification.
