The new laboratorial criterias in differential diagnostics

Abstract

Purpose: The retrieval of informative laboratorial criteria of acute myocardial infarction (AMI) and its aftereffects diagnostics for the reason of water homeostasis assessment and oxygen transportation blood function at patients with acute myocardial infarction (AMI) and postinfarction cardiosclerosis.Matherials and Methods: For the investigation were selected whole blood, plasma and erythrocytes of 200 patients. During the investigation were tested water fractions, content of 2,3-diphosphoglycerat, ectoglobular hemoglobin, the activity of glucose 6-phosphate dehydrogenase.Results: It was established different types of changes in water homeostasis at patients with acute myocardial infarction and postinfarction cardiosclerosis. It was revealed that in acute period of coronary catastrophe the level of bond water has risen both in whole blood and plasma that is compensator adaptive mechanism to prevent cellular dehydration. The prominent elevation of free fraction of water was found at patients with postinfarction cardiosclerosis that possibly is a leading reason of blood cells and cardiomyocytes hyperhydration.

Keywords

• water homeostasis
• acute myocardial infarction
• cardiosclerosis