Diabetes, Metabolic Syndrome and Obesity (Apr 2020)
Advances with Long Non-Coding RNAs in Diabetic Peripheral Neuropathy
Abstract
Men Wu, Yonghao Feng, Xiaohong Shi Department of Endocrinology, Jinshan Hospital, Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Xiaohong ShiDepartment of Endocrinology, Jinshan Hospital, Fudan University, 1508 Longxiang Road, Shanghai 201508, People’s Republic of ChinaEmail [email protected]: Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs longer than 200 nucleotides, which are defined as transcripts. The lncRNAs are involved in regulating gene expression at epigenetic, transcriptional, and post-transcriptional levels. Recent studies have found that lncRNA is closely related to many diseases like neurological diseases, endocrine and metabolic disorders. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus. In this review, we highlight the latest research related to lncRNAs in DPN.Keywords: long non-coding RNA, diabetes mellitus, diabetic peripheral neuropathy, diabetic neuropathic pain
