Detection of Jingmenviruses in Japan with Evidence of Vertical Transmission in Ticks
Daisuke Kobayashi,
Ryusei Kuwata,
Toshiya Kimura,
Hiroshi Shimoda,
Ryosuke Fujita,
Astri Nur Faizah,
Izumi Kai,
Ryo Matsumura,
Yudai Kuroda,
Shumpei Watanabe,
Sawako Kuniyoshi,
Takeo Yamauchi,
Mamoru Watanabe,
Yukiko Higa,
Toshihiko Hayashi,
Hiroto Shinomiya,
Ken Maeda,
Shinji Kasai,
Kyoko Sawabe,
Haruhiko Isawa
Affiliations
Daisuke Kobayashi
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Ryusei Kuwata
Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoinooka, Imabari City, Ehime 794-8555, Japan
Toshiya Kimura
Yawatahama Public Health Center, 1-3-37 Kitahana, Yawatahama City, Ehime 796-0048, Japan
Hiroshi Shimoda
Laboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi City, Yamaguchi 753-8515, Japan
Ryosuke Fujita
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Astri Nur Faizah
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Izumi Kai
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Ryo Matsumura
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Yudai Kuroda
Department of Veterinary Science, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Shumpei Watanabe
Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoinooka, Imabari City, Ehime 794-8555, Japan
Sawako Kuniyoshi
Tsushima Wildlife Conservation Center, 2956-5 Nishizato, Sago, Kamigata-machi, Tsushima City, Nagasaki 817-1603, Japan
Takeo Yamauchi
Laboratory of Entomology, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro City, Hokkaido 080-8555, Japan
Mamoru Watanabe
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Yukiko Higa
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Toshihiko Hayashi
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Hiroto Shinomiya
Ehime Prefectural Institute of Public Health and Environmental Science, 8-234 Sanban-cho, Matsuyama City, Ehime 790-0003, Japan
Ken Maeda
Department of Veterinary Science, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Shinji Kasai
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Kyoko Sawabe
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Haruhiko Isawa
Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Jingmen tick virus (JMTV) and the related jingmenvirus-termed Alongshan virus are recognized as globally emerging human pathogenic tick-borne viruses. These viruses have been detected in various mammals and invertebrates, although their natural transmission cycles remain unknown. JMTV and a novel jingmenvirus, tentatively named Takachi virus (TAKV), have now been identified during a surveillance of tick-borne viruses in Japan. JMTV was shown to be distributed across extensive areas of Japan and has been detected repeatedly at the same collection sites over several years, suggesting viral circulation in natural transmission cycles in these areas. Interestingly, these jingmenviruses may exist in a host tick species-specific manner. Vertical transmission of the virus in host ticks in nature was also indicated by the presence of JMTV in unfed host-questing Amblyomma testudinarium larvae. Further epidemiological surveillance and etiological studies are necessary to assess the status and risk of jingmenvirus infection in Japan.
