Nanoencapsulation of 3-Chloropropylaminobenzoate Derivatives with Potential Insecticidal Activity

Abstract

Aminobenzoic acid derivatives have shown various pharmacological properties, one of which is pesticide activity, giving these compounds the ability to work as alternatives to current pesticides. Nanotechnology could efficiently support the use of these compounds by encapsulating them in stable nanoformulations to improve their stability and effectiveness. In the present work, 3-chloropropylaminobenzoate derivatives were synthesised and evaluated against their effect on the viability of the insect cell line Sf9 (Spodoptera frugiperda), and nanoencapsulation studies of the most active compound were carried out. The most potent molecules reduced insect cell viability by around 40% at 100 µg/mL.

Keywords

• aminobenzoic acid derivatives
• aminobenzoates
• nanoencapsulation
• <i>Sf9</i> (<i>Spodoptera frugiperda</i>)
• insecticides