npj Digital Medicine (May 2018)

Scalable and accurate deep learning with electronic health records

  • Alvin Rajkomar,
  • Eyal Oren,
  • Kai Chen,
  • Andrew M. Dai,
  • Nissan Hajaj,
  • Michaela Hardt,
  • Peter J. Liu,
  • Xiaobing Liu,
  • Jake Marcus,
  • Mimi Sun,
  • Patrik Sundberg,
  • Hector Yee,
  • Kun Zhang,
  • Yi Zhang,
  • Gerardo Flores,
  • Gavin E. Duggan,
  • Jamie Irvine,
  • Quoc Le,
  • Kurt Litsch,
  • Alexander Mossin,
  • Justin Tansuwan,
  • De Wang,
  • James Wexler,
  • Jimbo Wilson,
  • Dana Ludwig,
  • Samuel L. Volchenboum,
  • Katherine Chou,
  • Michael Pearson,
  • Srinivasan Madabushi,
  • Nigam H. Shah,
  • Atul J. Butte,
  • Michael D. Howell,
  • Claire Cui,
  • Greg S. Corrado,
  • Jeffrey Dean

DOI
https://doi.org/10.1038/s41746-018-0029-1
Journal volume & issue
Vol. 1, no. 1
pp. 1 – 10

Abstract

Read online

Artificial intelligence: Algorithm predicts clinical outcomes for hospital inpatients Artificial intelligence outperforms traditional statistical models at predicting a range of clinical outcomes from a patient’s entire raw electronic health record (EHR). A team led by Alvin Rajkomar and Eyal Oren from Google in Mountain View, California, USA, developed a data processing pipeline for transforming EHR files into a standardized format. They then applied deep learning models to data from 216,221 adult patients hospitalized for at least 24 h each at two academic medical centers, and showed that their algorithm could accurately predict risk of mortality, hospital readmission, prolonged hospital stay and discharge diagnosis. In all cases, the method proved more accurate than previously published models. The authors provide a case study to serve as a proof-of-concept of how such an algorithm could be used in routine clinical practice in the future.