Stabilized Palladium Nanoparticles from Bis-(<i>N</i>-benzoylthiourea) Derived-Pd<sup>II</sup> Complexes as Efficient Catalysts for Sustainable Cross-Coupling Reactions in Water
Samet Poyraz,
H. Ali Döndaş,
Samet Belveren,
Senanur Taş,
Raquel Hidalgo-León,
José Trujillo-Sierra,
Lesly V. Rodríguez-Flórez,
Mª de Gracia Retamosa,
Ana Sirvent,
Mohammad Gholinejad,
Sara Sobhani,
José M. Sansano
Affiliations
Samet Poyraz
Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Çukurova University, Balcalı, Adana 01330, Türkiye
H. Ali Döndaş
Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Çukurova University, Balcalı, Adana 01330, Türkiye
Samet Belveren
Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Çukurova University, Balcalı, Adana 01330, Türkiye
Senanur Taş
Department of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Balcalı, Adana 01330, Türkiye
Raquel Hidalgo-León
Departamento de Química Orgánica, Instituto de Síntesis Orgánica (ISO), Centro de Innovación en Química Avanzada (ORFEO-CINQA), University of Alicante, P.O. Box 99, 03690 Alicante, Spain
José Trujillo-Sierra
Departamento de Química Orgánica, Instituto de Síntesis Orgánica (ISO), Centro de Innovación en Química Avanzada (ORFEO-CINQA), University of Alicante, P.O. Box 99, 03690 Alicante, Spain
Lesly V. Rodríguez-Flórez
Departamento de Química Orgánica, Instituto de Síntesis Orgánica (ISO), Centro de Innovación en Química Avanzada (ORFEO-CINQA), University of Alicante, P.O. Box 99, 03690 Alicante, Spain
Mª de Gracia Retamosa
Departamento de Química Orgánica, Instituto de Síntesis Orgánica (ISO), Centro de Innovación en Química Avanzada (ORFEO-CINQA), University of Alicante, P.O. Box 99, 03690 Alicante, Spain
Ana Sirvent
Departamento de Química Orgánica, Instituto de Síntesis Orgánica (ISO), Centro de Innovación en Química Avanzada (ORFEO-CINQA), University of Alicante, P.O. Box 99, 03690 Alicante, Spain
Mohammad Gholinejad
Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), P.O. Box 45195-1159, Zanjan 45137-66731, Iran
Sara Sobhani
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
José M. Sansano
Departamento de Química Orgánica, Instituto de Síntesis Orgánica (ISO), Centro de Innovación en Química Avanzada (ORFEO-CINQA), University of Alicante, P.O. Box 99, 03690 Alicante, Spain
Stable palladium (II) complexes, incorporating a double (N-benzoylthiourea) arrangement bonded to a complex heterocyclic scaffold, are used as precursors of catalytic species able to promote Suzuki–Miyaura, Mizoroki–Heck, Hiyama, Buchwald–Hartwig, Hirao and Sonogashira–Hagihara cross-coupling transformations in water. These sustainable processes are chemoselective and very versatile. The nanoparticles responsible for these catalytic reactions were analyzed and studied. Their usefulness is demonstrated after several tests and analyses. The heterogeneous character of this species in water was also confirmed.
