Unilateral rhino–orbital–cerebral mucormycosis with contralateral endogenous fungal endophthalmitis

Abstract

Hao Chi Ho,1,2 On Heong Liew,2 Swee Sew Teh,2 Hashim Hanizasurana,2 Mohtar Ibrahim,1 Ismail Shatriah1 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, 2Department of Ophthalmology, Hospital Selayang, Lebuhraya Selayang-Kepong, Selangor Darul Ehsan, Malaysia Abstract: Rhino–orbital–cerebral mucormycosis (ROCM) is an uncommon but fatal fungal infection. We report a rare case of unilateral ROCM with ipsilateral central retinal artery occlusion and contralateral choroiditis, which later progressed to endogenous fungal endophthalmitis. The patient was successfully treated with sinuses debridement, systemic liposomal amphotericin B, and intravitreal amphotericin B. The endophthalmitis completely resolved with good vision, but the ROCM eye remained blind due to central retinal artery occlusion. Keywords: rhino–orbital–cerebral mucormycosis, central retinal artery occlusion, chorioditis, endogenous fungal endophthalmitis, Rhizopus