Journal of Ardabil University of Medical Sciences (Dec 2013)
Effects of Inulin on Lipid Profile, Inflammation and Blood Pressure in Women with Type 2 Diabetes: A Randomized Controlled Trial
Abstract
Background & Objectives: Diabetes mellitus is a metabolic disease characterized by hyperglycemia together with biochemical alterations of lipid profile, insulin resistance and inflammation . Considering the high prevalence of hypertension, dyslipidemia and inflammation in type 2 diabetic patients, the aim of the present study was to investigate the effects of inulin on lipid profile, inflammation and blood pressure in women with type 2 diabetes. Methods: In this controlled, randomized clinical trial, 49 women with type 2 diabetes (fiber intake 0.04 ). Changes in diastolic blood pressures, LDL-c and HDL-c were not significant in inulin group compared with the maltodextrin group. A significant decrease in systolic, diastolic blood pressures, total cholesterol, triglyceride, LDL-c, hs-CRP and significant increase in HDL-c were observed in inulin group compared to baseline. Conclusions: Inulin supplementation may improve lipid profile, hs-CRP and blood pressure in women with type 2 diabetes.
