A REPORT OF 4 CASES OF CHROMOSOME ABNORMALITIES IN 115 FAMILIES WITH CONSANGUINEOUS MARRIAGE

Abstract

115 couples with consanguineous marriage, who had experienced reported abortions or still births either in their close relatives (3 couples) or themselves (1 couple) were exposed to genetic counseling (at the Shahid Akbarabadi hospital) Cytogenetic studied were carried out using both conventional staining and G.T.G banding for all the cases studied. The investigation demonstrated various forms of balanced translocation as fully discussed in the presented paper. During genetic counseling, information5 were also given to each couple regarding the Probability of having healthy or affected offspring’s, and also concerning prenatal diagnosis of the futures during pregnancies.

Keywords

• Chromosome study
• Genetic counseling