Nature Communications (Nov 2019)
Packaging and delivering enzymes by amorphous metal-organic frameworks
- Xiaoling Wu,
- Hua Yue,
- Yuanyu Zhang,
- Xiaoyong Gao,
- Xiaoyang Li,
- Licheng Wang,
- Yufei Cao,
- Miao Hou,
- Haixia An,
- Lin Zhang,
- Sai Li,
- Jingyuan Ma,
- He Lin,
- Yanan Fu,
- Hongkai Gu,
- Wenyong Lou,
- Wei Wei,
- Richard N. Zare,
- Jun Ge
Affiliations
- Xiaoling Wu
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- Hua Yue
- State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences
- Yuanyu Zhang
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- Xiaoyong Gao
- State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences
- Xiaoyang Li
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- Licheng Wang
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- Yufei Cao
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- Miao Hou
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- Haixia An
- State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences
- Lin Zhang
- Department of Biochemical Engineering and Key Laboratory of Systems Bioengineering of the Ministry of Education, School of Chemical Engineering and Technology, Tianjin University
- Sai Li
- Key Laboratory of Protein Science, Ministry of Education, School of Life Sciences, Tsinghua University
- Jingyuan Ma
- Shanghai Synchrotron Radiation Facility, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences
- He Lin
- Shanghai Synchrotron Radiation Facility, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences
- Yanan Fu
- Shanghai Synchrotron Radiation Facility, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences
- Hongkai Gu
- State Key Laboratory of Superhard Materials, Jilin University
- Wenyong Lou
- School of Food Science and Engineering, South China University of Technology
- Wei Wei
- State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences
- Richard N. Zare
- Department of Chemistry, Fudan University, Jiangwan Campus
- Jun Ge
- Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University
- DOI
- https://doi.org/10.1038/s41467-019-13153-x
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 8
Abstract
For packaging enzymes into metal–organic frameworks (MOFs), crystalline MOFs are usually used. Here, the authors encapsulated enzymes in amorphous MOFs a via one-pot co-precipitation process under ambient condition, which led to higher enzymatic activity than in a corresponding crystalline MOF composite.
