Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study
Xin Min,
Zheng Zhang,
Yanwei Chen,
Shuangshuang Zhao,
Jingwen Ge,
Huajiao Zhao,
Yun Cai,
Hui Chen,
Jun Shao,
Yanfei Jing,
Baoding Chen
Affiliations
Xin Min
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Zheng Zhang
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Yanwei Chen
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Shuangshuang Zhao
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Jingwen Ge
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Huajiao Zhao
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Yun Cai
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Hui Chen
Department of Medical Ultrasound, Changzhou First People’s Hospital and The Third Affiliated Hospital of Soochow University
Jun Shao
Department of Medical Ultrasound, The First People’s Hospital of Kunshan Affiliated to Jiangsu University
Yanfei Jing
Department of Medical Ultrasound, The Fifth People’s Hospital of Wuxi, The Medical School of Jiangnan University
Baoding Chen
Department of Medical Ultrasound, Affiliated Hospital of Jiangsu University
Abstract Purpose To compare the therapeutic efficacy and safety of microwave ablation (MWA) and lauromacrogol injection for ablation (LIA) for benign predominantly cystic thyroid nodules. Materials and methods In this retrospective study, 85 patients with predominantly cystic thyroid nodules (PCTNs) who underwent microwave ablation (MWA) or lauromacrogol injection for ablation (LIA) between June 2019 and August 2022 at three hospitals were included in our research. Forty-six patients were treated with microwave ablation, and thirty-nine patients were treated with lauromacrogol injection for ablation. The baseline characteristics, nodal volume, volume reduction rate (VRR), and incidence of postoperative complications were compared between these two groups. Results After treatment, there were significant differences in the thyroid nodule volume and the volume reduction rate (VRR) at different follow-up times between the groups (p 0.05). Of note, no serious intraoperative or postoperative complications occurred in the corresponding group. Conclusion MWA and LIA are very effective and safe strategies for the treatment of predominantly cystic thyroid nodules. However, LIA is more advantageous in that it is less expensive and has a shorter length of hospital stay than MWA.
