POLYRETINA restores light responses in vivo in blind Göttingen minipigs

Paola Vagni; Marta Jole Ildelfonsa Airaghi Leccardi; Charles-Henri Vila; Elodie Geneviève Zollinger; Golnaz Sherafatipour; Thomas J. Wolfensberger; Diego Ghezzi

doi:10.1038/s41467-022-31180-z

Nature Communications (Jun 2022)

POLYRETINA restores light responses in vivo in blind Göttingen minipigs

Paola Vagni,
Marta Jole Ildelfonsa Airaghi Leccardi,
Charles-Henri Vila,
Elodie Geneviève Zollinger,
Golnaz Sherafatipour,
Thomas J. Wolfensberger,
Diego Ghezzi

Affiliations

Paola Vagni: Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne
Marta Jole Ildelfonsa Airaghi Leccardi: Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne
Charles-Henri Vila: Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne
Elodie Geneviève Zollinger: Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne
Golnaz Sherafatipour: Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne
Thomas J. Wolfensberger: Department of Ophthalmology, University of Lausanne, Hôpital Ophtalmique Jules-Gonin, Fondation Asile des Aveugles
Diego Ghezzi: Medtronic Chair in Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne

DOI: https://doi.org/10.1038/s41467-022-31180-z
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 14

Abstract

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Retinal prostheses hold potential for artificial vision in blind people. Here, authors show that POLYRETINA, a large and high-density photovoltaic epiretinal device, restores light-evoked cortical responses in blind Göttingen minipigs at safe irradiance levels.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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