Physics and Imaging in Radiation Oncology (Jul 2024)
Bringing online adaptive radiotherapy to a standard C-arm linac
- Maureen L. Groot Koerkamp,
- Gijsbert H. Bol,
- Petra S. Kroon,
- Lean L. Krikke,
- Tessa Harderwijk,
- Annelies J. Zoetelief,
- Annick Scheeren,
- Stefan van der Vegt,
- Annika Plat,
- Jochem Hes,
- Ineke B.A. van Gasteren,
- Esmee R.T. Renders,
- Reijer H.A. Rutgers,
- Saskia W. Kok,
- Joost van Kaam,
- Geja J. Schimmel-de Kogel,
- Gonda G. Sikkes,
- Dennis Winkel,
- Michael J. van Rijssel,
- André J.M. Wopereis,
- Kübra Ishakoglu,
- Juus L. Noteboom,
- Jochem R.N. van der Voort van Zyp,
- Naomi Beck,
- Timo F.W. Soeterik,
- Sandrine M.G. van de Pol,
- Wietse S.C. Eppinga,
- Corine A. van Es,
- Bas W. Raaymakers
Affiliations
- Maureen L. Groot Koerkamp
- Corresponding author at: UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands.; Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Gijsbert H. Bol
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Petra S. Kroon
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Lean L. Krikke
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Tessa Harderwijk
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Annelies J. Zoetelief
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Annick Scheeren
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Stefan van der Vegt
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Annika Plat
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Jochem Hes
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Ineke B.A. van Gasteren
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Esmee R.T. Renders
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Reijer H.A. Rutgers
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Saskia W. Kok
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Joost van Kaam
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Geja J. Schimmel-de Kogel
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Gonda G. Sikkes
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Dennis Winkel
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Michael J. van Rijssel
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- André J.M. Wopereis
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Kübra Ishakoglu
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Juus L. Noteboom
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Jochem R.N. van der Voort van Zyp
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Naomi Beck
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Timo F.W. Soeterik
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Sandrine M.G. van de Pol
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Wietse S.C. Eppinga
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Corine A. van Es
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Bas W. Raaymakers
- Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands
- Journal volume & issue
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Vol. 31
p. 100597
Abstract
Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.
