Epigenetic Reprogramming of Human Hepatoma Cells: A Low-Cost Option for Drug Metabolism Assessment

• Luc Gailhouste,
• Lee Chuen Liew,
• Ken Yasukawa,
• Keitaro Hagiwara,
• Norihiko Iwazaki,
• Yasuhiro Yamada,
• Izuho Hatada,
• Takahiro Ochiya

Affiliations

Luc Gailhouste

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan

Lee Chuen Liew

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan

Ken Yasukawa

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan

Keitaro Hagiwara

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan

Norihiko Iwazaki

Drug Metabolism and Pharmacokinetics Research Laboratories, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan

Yasuhiro Yamada

Drug Metabolism and Pharmacokinetics Research Laboratories, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan

Izuho Hatada

Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan

Takahiro Ochiya

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan