Stem cells of the suture mesenchyme in craniofacial bone development, repair and regeneration

Takamitsu Maruyama; Jaeim Jeong; Tzong-Jen Sheu; Wei Hsu

doi:10.1038/ncomms10526

Nature Communications (Feb 2016)

Stem cells of the suture mesenchyme in craniofacial bone development, repair and regeneration

Takamitsu Maruyama,
Jaeim Jeong,
Tzong-Jen Sheu,
Wei Hsu

Affiliations

Takamitsu Maruyama: Department of Biomedical Genetics, Center for Oral Biology, University of Rochester Medical Center
Jaeim Jeong: Department of Biomedical Genetics, Center for Oral Biology, University of Rochester Medical Center
Tzong-Jen Sheu: Center for Musculoskeletal Research, University of Rochester Medical Center
Wei Hsu: Department of Biomedical Genetics, Center for Oral Biology, University of Rochester Medical Center

DOI: https://doi.org/10.1038/ncomms10526
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 11

Abstract

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The suture mesenchyme has been postulated to act as the niche for stem cells for calvarial bones but the identity of the stem cells is unknown. Here, Maruyama et al.suggest that Axin2 expressing cells act as stem cells not only in craniofacial bone development and homeostasis but in injury-induced repair.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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