NON-SPECIFIC AORTO-ARTERIITIS IN FEMALES: PECULIARITIES OF LIPID-HORMONAL INTERRELATIONS

Abstract

Objective. To study of lipid-hormonal interrelations in women with nonspecific aorloarteriitis (NAA) depending on age and activity's degree of immuno-infiamatory process. Materials. 85 women at the age of 16-55 were investigated, level of lipids and sexual hormones was studied in blood plasma. Results. In patients with NAA antiatherogenic system of lipids above atherogenic was predominanate. Negative correlation was found between levels of estradiol and progesterone and level of atherogenic lipoproteins. It was determined, that considerable reduction of level of total cholesterol and LDLP occurs as far as increasing of activity of immuno-inflammatory process. Conclusion. The levels of lipids are controled by condition of sexual hormones’ balance. Low level of total cholesterol and LDLP is able to be considered as an additional marker of disease’s activity ill women with NAA.

Keywords

• nonspecific aortoartcriitis
• women
• estradiol
• progesterone
• lipids