Antiviral Preparation in Complex Therapy of Acute Intestinal Infections of Viral and Viral-Bacterial Etiology in Children

Abstract

We observed 70 patients: 40 patients with rotavirus infection and 30 patients with viral-bacterial intestinal co-infection. The age of the patient varied between 2 and 10 years. It was found that introduction of Arbidol in doses that correspond the patients’ age in 5-day course of complex therapy reliably reduces the duration of acute period of the disease: at rotavirus monoinfection (p < 0,001) and at viral and bacterial (p < 0,05). The time of elimination of rotavirus from patients’ stool also reduced significantly. In the group of patients who received the treatment with Arbidol, there was a clear tendency towards normalization of the quantitative content (CFU/g) of normal flora of the intestine, but only some of its representatives — lactobacilli and enterococci.

Keywords

• rotavirus
• аrbidol
• children
• microbiocenosis