Wolfram Syndrome

Abstract

Two unrelated patients with Wolfram syndrome (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) in whom MRIs of the brain provide evidence of a diffuse neurodegenerative process are reported from the Departments of Neurology and Ophthalmology, University of California at San Francisco, CA.

Keywords

• wolfram syndrome
• cerebellum
• hyporeflexia