Connectivity and network state-dependent recruitment of long-range VIP-GABAergic neurons in the mouse hippocampus

Ruggiero Francavilla; Vincent Villette; Xiao Luo; Simon Chamberland; Einer Muñoz-Pino; Olivier Camiré; Kristina Wagner; Viktor Kis; Peter Somogyi; Lisa Topolnik

doi:10.1038/s41467-018-07162-5

Nature Communications (Nov 2018)

Connectivity and network state-dependent recruitment of long-range VIP-GABAergic neurons in the mouse hippocampus

Ruggiero Francavilla,
Vincent Villette,
Xiao Luo,
Simon Chamberland,
Einer Muñoz-Pino,
Olivier Camiré,
Kristina Wagner,
Viktor Kis,
Peter Somogyi,
Lisa Topolnik

Affiliations

Ruggiero Francavilla: Neuroscience Axis, CHU de Québec Research Center, Université Laval
Vincent Villette: Neuroscience Axis, CHU de Québec Research Center, Université Laval
Xiao Luo: Neuroscience Axis, CHU de Québec Research Center, Université Laval
Simon Chamberland: Department of Biochemistry, Microbiology and Bio-informatics, Université Laval
Einer Muñoz-Pino: Neuroscience Axis, CHU de Québec Research Center, Université Laval
Olivier Camiré: Neuroscience Axis, CHU de Québec Research Center, Université Laval
Kristina Wagner: Department of Pharmacology, Oxford University
Viktor Kis: Department of Pharmacology, Oxford University
Peter Somogyi: Department of Pharmacology, Oxford University
Lisa Topolnik: Neuroscience Axis, CHU de Québec Research Center, Université Laval

DOI: https://doi.org/10.1038/s41467-018-07162-5
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 17

Abstract

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Long-range GABAergic hippocampal neurons project to cortical and subcortical areas, while vasoactive intestinal peptide (VIP+) interneurons can inhibit other GABAergic neurons. Here, authors discover a VIP+, long-range projecting GABAergic neuron whose activity is associated with quiet wakefulness.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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