Atmospheric Measurement Techniques (Jan 2025)
An interlaboratory comparison to quantify oxidative potential measurement in aerosol particles: challenges and recommendations for harmonisation
- P. A. Dominutti,
- J.-L. Jaffrezo,
- A. Marsal,
- T. Mhadhbi,
- R. Elazzouzi,
- C. Rak,
- F. Cavalli,
- J.-P. Putaud,
- A. Bougiatioti,
- N. Mihalopoulos,
- N. Mihalopoulos,
- D. Paraskevopoulou,
- I. Mudway,
- I. Mudway,
- A. Nenes,
- A. Nenes,
- K. R. Daellenbach,
- C. Banach,
- S. J. Campbell,
- H. Cigánková,
- D. Contini,
- G. Evans,
- M. Georgopoulou,
- M. Ghanem,
- D. A. Glencross,
- D. A. Glencross,
- M. R. Guascito,
- M. R. Guascito,
- H. Herrmann,
- S. Iram,
- M. Jovanović,
- M. Jovašević-Stojanović,
- M. Kalberer,
- I. M. Kooter,
- S. E. Paulson,
- A. Patel,
- A. Patel,
- A. Patel,
- E. Perdrix,
- M. C. Pietrogrande,
- P. Mikuška,
- J.-J. Sauvain,
- K. Seitanidi,
- P. Shahpoury,
- E. J. d. S. Souza,
- S. Steimer,
- S. Steimer,
- S. Stevanovic,
- G. Suarez,
- P. S. G. Subramanian,
- B. Utinger,
- M. F. van Os,
- V. Verma,
- X. Wang,
- R. J. Weber,
- Y. Yang,
- X. Querol,
- G. Hoek,
- R. M. Harrison,
- R. M. Harrison,
- G. Uzu
Affiliations
- P. A. Dominutti
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- J.-L. Jaffrezo
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- A. Marsal
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- T. Mhadhbi
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- R. Elazzouzi
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- C. Rak
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- F. Cavalli
- European Commission, Joint Research Centre (JRC), Ispra, Italy
- J.-P. Putaud
- European Commission, Joint Research Centre (JRC), Ispra, Italy
- A. Bougiatioti
- Institute for Environmental Research and Sustainable Development, National Observatory of Athens, Lofos Koufou, P. Penteli, Athens, 15236, Greece
- N. Mihalopoulos
- Institute for Environmental Research and Sustainable Development, National Observatory of Athens, Lofos Koufou, P. Penteli, Athens, 15236, Greece
- N. Mihalopoulos
- Environmental Chemical Processes Laboratory, Department of Chemistry, University of Crete, Heraklion, 71003, Greece
- D. Paraskevopoulou
- Institute for Environmental Research and Sustainable Development, National Observatory of Athens, Lofos Koufou, P. Penteli, Athens, 15236, Greece
- I. Mudway
- MRC Centre for Environment and Health, Environmental Research Group, Imperial College London, 86 Wood Lane, London, W12 0BZ, UK
- I. Mudway
- National Institute of Health Research, Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
- A. Nenes
- Center for the Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, 26504, Greece
- A. Nenes
- Laboratory of Atmospheric Processes and their Impacts, Institute of Environmental Engineering, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland
- K. R. Daellenbach
- Laboratory of Atmospheric Chemistry, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland
- C. Banach
- Department of Atmospheric and Oceanic Sciences, University of California at Los Angeles, 520 Portola Plaza, Los Angeles, CA 90095, United States
- S. J. Campbell
- MRC Centre for Environment and Health, Environmental Research Group, Imperial College London, 86 Wood Lane, London, W12 0BZ, UK
- H. Cigánková
- Department of Environmental Analytical Chemistry, Institute of Analytical Chemistry, Czech Academy of Sciences, Veveří 97, 60200 Brno, Czech Republic
- D. Contini
- Institute of Atmospheric Sciences and Climate, ISAC-CNR, Str. Prv. Lecce-Monteroni km 1.2, 73100 Lecce, Italy
- G. Evans
- Southern Ontario Centre for Atmospheric Aerosol Research, University of Toronto, Toronto, M5S 3E5, Canada
- M. Georgopoulou
- Center for the Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, 26504, Greece
- M. Ghanem
- Department of Pollutant Metrology, Institut National de Recherche et de Sécurité (INRS), 54500 Vandœuvre-lès-Nancy, France
- D. A. Glencross
- MRC Centre for Environment and Health, Environmental Research Group, Imperial College London, 86 Wood Lane, London, W12 0BZ, UK
- D. A. Glencross
- National Institute of Health Research, Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
- M. R. Guascito
- Institute of Atmospheric Sciences and Climate, ISAC-CNR, Str. Prv. Lecce-Monteroni km 1.2, 73100 Lecce, Italy
- M. R. Guascito
- Department of Biological and Environmental Sciences and Technologies (DISTEBA), University of Salento, 73100 Lecce, Italy
- H. Herrmann
- Atmospheric Chemistry Department (ACD), Leibniz Institute for Tropospheric Research (TROPOS), Permoserstraße 15, 04318 Leipzig, Germany
- S. Iram
- School of Engineering, Deakin University, Geelong, 3216 Victoria, Australia
- M. Jovanović
- Vinča Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade, 11 351 Belgrade, Serbia
- M. Jovašević-Stojanović
- Vinča Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade, 11 351 Belgrade, Serbia
- M. Kalberer
- Department of Environmental Sciences, University of Basel, 4056 Basel, Switzerland
- I. M. Kooter
- TNO Environmental Modelling, Sensing and Analysis, Princetonlaan 6-8, 3584 CB Utrecht, the Netherlands
- S. E. Paulson
- Department of Atmospheric and Oceanic Sciences, University of California at Los Angeles, 520 Portola Plaza, Los Angeles, CA 90095, United States
- A. Patel
- Department of Environmental Science, Stockholm University, Stockholm, 11418, Sweden
- A. Patel
- Bolin Centre for Climate Research, Stockholm, 11418, Sweden
- A. Patel
- now at: Bagchi School of Public Health, Ahmedabad University, Ahmedabad 380009, Gujarat, India
- E. Perdrix
- IMT Nord Europe, Institut Mines-Télécom, Univ. Lille, Centre for Energy and Environment, 59000 Lille, France
- M. C. Pietrogrande
- Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Via Fossato di Mortara 17/19, 44121 Ferrara, Italy
- P. Mikuška
- Department of Environmental Analytical Chemistry, Institute of Analytical Chemistry, Czech Academy of Sciences, Veveří 97, 60200 Brno, Czech Republic
- J.-J. Sauvain
- Center for Primary Care and Public Health (Unisanté), Department of Occupational and Environment Health (DSTE), University of Lausanne, Lausanne, Switzerland
- K. Seitanidi
- Center for the Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, 26504, Greece
- P. Shahpoury
- Environmental and Life Sciences, Trent University, Peterborough, Canada
- E. J. d. S. Souza
- Atmospheric Chemistry Department (ACD), Leibniz Institute for Tropospheric Research (TROPOS), Permoserstraße 15, 04318 Leipzig, Germany
- S. Steimer
- Department of Environmental Science, Stockholm University, Stockholm, 11418, Sweden
- S. Steimer
- Bolin Centre for Climate Research, Stockholm, 11418, Sweden
- S. Stevanovic
- School of Engineering, Deakin University, Geelong, 3216 Victoria, Australia
- G. Suarez
- Center for Primary Care and Public Health (Unisanté), Department of Occupational and Environment Health (DSTE), University of Lausanne, Lausanne, Switzerland
- P. S. G. Subramanian
- Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, 205 North Mathews Avenue, Urbana, IL 61801, United States
- B. Utinger
- Department of Environmental Sciences, University of Basel, 4056 Basel, Switzerland
- M. F. van Os
- TNO Environmental Modelling, Sensing and Analysis, Princetonlaan 6-8, 3584 CB Utrecht, the Netherlands
- V. Verma
- Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, 205 North Mathews Avenue, Urbana, IL 61801, United States
- X. Wang
- Southern Ontario Centre for Atmospheric Aerosol Research, University of Toronto, Toronto, M5S 3E5, Canada
- R. J. Weber
- School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, GA 30332, United States
- Y. Yang
- School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, GA 30332, United States
- X. Querol
- Institute of Environmental Assessment and Water Research (IDAEA-CSIC), 08034 Barcelona, Spain
- G. Hoek
- Institute for Risk Assessment Sciences, Utrecht University, Utrecht, 3584CM, the Netherlands
- R. M. Harrison
- Division of Environmental Health and Risk Management, School of Geography, Earth and Environmental Sciences, Edgbaston, Birmingham, B15 2TT, UK
- R. M. Harrison
- Department of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
- G. Uzu
- University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
- DOI
- https://doi.org/10.5194/amt-18-177-2025
- Journal volume & issue
-
Vol. 18
pp. 177 – 195
Abstract
This paper presents the findings from a collaborative interlaboratory comparison exercise designed to assess oxidative potential (OP) measurements conducted by 20 laboratories worldwide. This study represents an innovative effort as the first exercise specifically aimed at harmonising this type of OP assay, setting a new benchmark in the field. Over the last decade, there has been a noticeable increase in OP studies, with numerous research groups investigating the effects of exposure to air pollution particles through the evaluation of OP levels. However, the absence of standardised methods for OP measurements has resulted in variability in results across different groups, rendering meaningful comparisons challenging. To address this issue, this study engages in an international effort to compare OP measurements using a simplified method (with a dithiothreitol (DTT) assay). Here, we quantify the OP in liquid samples to focus on the protocol measurement itself, while future international OP interlaboratory comparisons (ILCs) should aim to assess the whole chain process, including the sample extraction. We analyse the similarities and discrepancies observed in the results, identifying the critical parameters (such as the instrument used, the use of a simplified protocol, the delivery and analysis time) that could influence OP measurements and provide recommendations for future studies and interlaboratory comparisons even if other crucial aspects, such as sampling PM methods, sample storage, extraction methods and conditions, and the evaluation of other OP assays, still need to be standardised. This collaborative approach enhances the robustness of the OP DTT assay and paves the way for future studies to build on a unified framework. This pioneering work concludes that interlaboratory comparisons provide essential insights into the OP metric and are crucial to move toward the harmonisation of OP measurements.
