Nature Communications (Mar 2017)

Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage

  • Jesús Mosquera,
  • Bartosz Szyszko,
  • Sarah K. Y. Ho,
  • Jonathan R. Nitschke

DOI
https://doi.org/10.1038/ncomms14882
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 6

Abstract

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One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from proteolysis.