Nature Communications (Mar 2017)
Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage
Abstract
One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from proteolysis.