A modular effector with a DNase domain and a marker for T6SS substrates

Biswanath Jana; Chaya M. Fridman; Eran Bosis; Dor Salomon

doi:10.1038/s41467-019-11546-6

Nature Communications (Aug 2019)

A modular effector with a DNase domain and a marker for T6SS substrates

Biswanath Jana,
Chaya M. Fridman,
Eran Bosis,
Dor Salomon

Affiliations

Biswanath Jana: Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University
Chaya M. Fridman: Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University
Eran Bosis: Department of Biotechnology Engineering, ORT Braude College of Engineering
Dor Salomon: Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University

DOI: https://doi.org/10.1038/s41467-019-11546-6
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 12

Abstract

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Bacteria deliver toxic effectors via type VI secretion systems (T6SSs) to dominate competitors. Here, the authors identify a Vibrio antibacterial effector that contains a new DNase toxin domain and a domain of unknown function that can be used as a marker to identify new T6SS effectors.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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