Mathematical Biosciences and Engineering (Jan 2023)

Dynamics of a stochastic hepatitis B virus transmission model with media coverage and a case study of China

  • Jiying Ma,
  • Shasha Ma

DOI
https://doi.org/10.3934/mbe.2023145
Journal volume & issue
Vol. 20, no. 2
pp. 3070 – 3098

Abstract

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Hepatitis B virus (HBV) infection is a global public health problem and there are 257 million people living with chronic HBV infection throughout the world. In this paper, we investigate the dynamics of a stochastic HBV transmission model with media coverage and saturated incidence rate. Firstly, we prove the existence and uniqueness of positive solution for the stochastic model. Then the condition on the extinction of HBV infection is obtained, which implies that media coverage helps to control the disease spread and the noise intensities on the acute and chronic HBV infection play a key role in disease eradication. Furthermore, we verify that the system has a unique stationary distribution under certain conditions, and the disease will prevail from the biological perspective. Numerical simulations are conducted to illustrate our theoretical results intuitively. As a case study, we fit our model to the available hepatitis B data of mainland China from 2005 to 2021.

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