Тонкие химические технологии (Dec 2017)

PHYTOPREPARATIONS IN THE PREVENTION AND TREATMENT OF URATE NEPHROLITHIASIS

  • N. G. Chaban,
  • A. Yu. Putin,
  • L. M. Rapoport,
  • T. M. Buslaeva

DOI
https://doi.org/10.32362/2410-6593-2017-12-6-39-45
Journal volume & issue
Vol. 12, no. 6
pp. 39 – 45

Abstract

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The composition, structure and specific features of urate calculi are discussed in the article. It was shown that they consist of 95% of uric acid and its salts on an average by the X-ray phase and energy dispersive analysis of a number of samples extracted from the urinary tract of 24 urological patients. The mechanism of formation of urate stones is considered. It is noted that urate stones are formed at a urine under pH below 5.5. The factors reducing the development of urinary urolythiasis and uraturia are indicated. The drugs commonly used for the treatment and prevention of urate nephrolithiasis are listed. The role of phytotherapy is underlined in the treatment of urolithiasis in general and urate nephrolithiasis in particular. It is concluded that the composition of plant compositions should include natural compounds of the alkaloid class. The most promising compositions of medicinal plants were determined, and the effect of herbal extracts of various compositions on the pH of the solution and the loss of stone mass

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