Data for stable formulation of steroid hormone receptor-targeted liposomes for cancer therapeutics

Abstract

A detailed description of steroid hormone ligand containing liposomes and their stability has been given. Liposomes were complexed with β-gal DNA and used to transfect cancer and non-cancer cells. The stability of the liposomes and lipoplexes were analysed using dynamic light scattering and DNA-binding gel images. The formulations were used to assess the delivery of anticancer gene, p53 in cancer cells. The dataset consists of DNA-binding gel images, transfection, cytotoxicity and reverse transcriptase PCR images. Keywords: Steroid hormone, Liposomes, Lipoplexes, Anti-cancer gene, Transfection, Cytotoxicity