Pengaruh Pasta Gigi Mengandung Xylitol terhadap Pertumbuhan Streptococcus mutans Serotip C In Vitro

Abstract

Streptococcus mutans serotype C is a major causative agent to caries and is found predominantly in dental plaque and saliva. Dentrifice containing xylitol has been shown to inhibit the growth of mutans streptococci. The aim of the study was to determine in vitro the influence of dentrifice containing xylitol on S. mutans serotype C. The solution of dentrifice containing xylitol was first diluted with sterile aquadest at 1:1, and then to concentration of 100%, 10%, 1%, 0.1%, 0.01% and 0.001%, also with positive and negative controls. These solutions were exposed to S. mutans serotype C by diffusion and dilution method. The results of the study show that the inhibition zone formed at concentrations of 10% and 100%. There was a significant positive correlation betwee the concentration of the dentrifice and the growth of mutans streptococci (p<0.05), with MBC point at 10%. In conclusion, dentrifice containing xylitol has an antibacterial effect and can inhibit the growth of S. mutans serotype C. Increasing concentration of dentrifice containing xylitol increases the sze of the inhibition zone.

Keywords

• dentrifice containing xylitol
• streptococcus mutans serotype c
• antibacterial effect