Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2022)

Clinical utility of methicillin-resistant Staphylococcus aureus nasal polymerase chain reaction (PCR) assays beyond respiratory infections

  • Haley M. Noeldner,
  • Zachary J. Bliek,
  • Nephi E. Jones,
  • Ryan D. Prusa,
  • Melissa S. Wilkinson,
  • Amanda M. Bushman,
  • Rossana Rosa

DOI
https://doi.org/10.1017/ash.2022.256
Journal volume & issue
Vol. 2

Abstract

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We estimated the predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal polymerase chain reaction (PCR) for blood, bone, and soft-tissue cultures. The specificities were 88.8%, 88.5%, and 92.7% for all cultures, blood cultures, and bone and soft-tissue cultures respectively, and the negative predictive values were 99.3%, 99.8%, and 92.7% respectively.