International Journal of Nephrology and Renovascular Disease (Apr 2022)

Incremental Hemodialysis: What We Know so Far

  • Soi V,
  • Faber MD,
  • Paul R

Journal volume & issue
Vol. Volume 15
pp. 161 – 172

Abstract

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Vivek Soi,1,2 Mark D Faber,1,2 Ritika Paul1 1Division of Nephrology and Hypertension, Henry Ford Hospital, Detroit, MI, USA; 2Wayne State University School of Medicine, Detroit, MI, USACorrespondence: Vivek Soi, Email [email protected]: Traditionally, patients that develop progressive chronic kidney disease in need of kidney replacement therapy are prescribed thrice weekly in-center hemodialysis sessions at the beginning of therapy. This empiric prescription is based on historic trials that were comprised of mostly prevalent patients. Incremental hemodialysis is the process of performing 500 mL/day, although these measures have been deemed conservative. A significant amount of retrospective and registry data has been supportive of initiating incremental hemodialysis and several pilot studies have shown the feasibility of implementing such an approach. Larger, randomized control trials are needed to fully evaluate safety and efficacy to allow for more widespread acceptance of this patient-centered approach to chronic kidney disease.Keywords: hemodialysis, incremental dialysis, twice-weekly

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