European Journal of Case Reports in Internal Medicine (Dec 2021)

Immune Thrombocytopenia: A Rare Presentation of Pulmonary Sarcoidosis

  • Mariana da Silva Leal,
  • Carolina Amado,
  • Bárbara Paracana,
  • Flávio Pereira,
  • Mariana Sousa,
  • Aurora Mendes

DOI
https://doi.org/10.12890/2021_003060

Abstract

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Thrombocytopenia may be the initial presentation of sarcoidosis, which is a systemic granulomatous disorder. Various pathophysiological mechanisms have been identified. Immune thrombocytopenia often has a severe presentation but may respond favourably to immunosuppressive therapy. There are no guidelines for the treatment of thrombocytopenia in sarcoidosis. However, in emergency situations with major bleeding, it seems reasonable to apply the current guidelines recommended for immune thrombocytopenia. The authors report a case of sarcoidosis presenting with severe thrombocytopenia, petechial rash, and nasal and gingival bleeding.

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