Alzheimer’s & Dementia: Translational Research & Clinical Interventions (Jan 2020)

Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease

  • Stacie Weninger,
  • Bjorn Sperling,
  • Robert Alexander,
  • Magnus Ivarsson,
  • Fiona M. Menzies,
  • Peter Powchik,
  • Christopher J. Weber,
  • C. Anthony Altar,
  • Ronald G. Crystal,
  • Stephen J. Haggarty,
  • Jeanne Loring,
  • Lisa J. Bain,
  • Maria C. Carrillo

DOI
https://doi.org/10.1002/trc2.12090
Journal volume & issue
Vol. 6, no. 1
pp. n/a – n/a

Abstract

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Abstract As knowledge of Alzheimer's disease (AD) progression improves, the field has recognized the need to diversify the pipeline, broaden strategies and approaches to therapies, as well as delivery mechanisms. A better understanding of the earliest biological processes of AD/dementia would help inform drug target selection. Currently there are a number of programs exploring these alternate avenues. This meeting will allow experts in the field (academia, industry, government) to provide perspectives and experiences that can help elucidate what the pipeline looks like today and what avenues hold promise in developing new therapies across the stages of AD. The focus here is on Active Immunotherapies and Alternative Therapeutic Modalities. This topic includes active vaccines, antisense oligomers, and cell‐based therapy among others, and highlights new clinical developments that utilize these modalities.