International Journal of Ophthalmology (Sep 2023)

Changes of retinal vessel density in low to moderate myopic eyes with orthokeratology evaluated by optical coherence tomography angiography

  • Jia-Hui Shi,
  • Yi-Ping Zhao,
  • Gang Liu,
  • Xin-Yi Huang,
  • Li-Li Lang,
  • Wan-Cheng Jia,
  • Ji-Li Chen

DOI
https://doi.org/10.18240/ijo.2023.09.19
Journal volume & issue
Vol. 16, no. 9
pp. 1512 – 1520

Abstract

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AIM: To explore the effect of orthokeratology (OK) fitting on retinal vessel density in low to moderate myopia adolescents by using optical coherence tomography angiography. METHODS: Children aged 10 to 14y with a cycloplegic spherical equivalent refraction of −0.50 diopter (D) to −5.00 D and astigmatism with more than −1.50 D were recruited. The enrolled adolescents were divided into OK group and spectacle group. During regular follow-up, adolescents were measured respectively at pre-wear, 1, 3, and 6mo after treatment. The follow-up included uncorrected distance visual acuity (UDVA), axial length (AL), superficial capillary plexus density (SCPD), deep capillary plexus density (DCPD), central retinal thickness (CRT), foveal avascular zone area (FAZ-A), foveal avascular zone perimeter (FAZ-P) and foveal vessel density in a 300-µm-wide region around foveal avascular zone (FD-300). The collected data were analyzed using statistical methods. RESULTS: By one month, SCPD significantly increased in the fovea and superior retina, and DCPD significantly increased inferiorly in OK group compared to spectacle group (P0.05). OK group showed a significant improvement in UDVA after wearing OK, compared to spectacle group (P0.05). CONCLUSION: Short-term OK worn can increase local retinal vessel density in adolescents with low-to-moderate myopia.

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