Variation characteristics and influencing factors of choroidal thickness of subfoveal fovea in children with myopia

Abstract

AIM: To study the characteristics and related influencing factors of subfoveal choroidal thickness(SFCT)changing with time in children with myopia. METHODS: Totally 60 eyes of 60 children with myopia aged 6-15 years old who were admitted to the Eye Hospital of Nanchang University from July 2018 to September 2018 were included. IOP, axial length, equivalent spherical degree and SFCT were measured at baseline and 6mo of follow-up, respectively. Analyze the changes of the above-mentioned eye parameters and related influencing factors of SFCT. RESULTS: Compared with baseline, follow-up for 6mo, myopic children's SFCT decreased by 8±14μm(P<0.001), the axial length increased by 0.15±0.16mm(P<0.001), and the equivalent spherical degree increased by -0.34±0.33D(P<0.001), and there is a significant correlation between the SFCT change value and the axial length and equivalent spherical power change value(rs=-0.701, 0.633, both P<0.001), indicating faster axial growth and myopia increasing is related to more thinning of the membrane thickness. Multiple linear regression analysis shows that SFCT is significantly correlated with axial length(P=0.001).CONCLUSION: The SFCT of myopic children becomes thinner over time, and the axial length is negatively correlated with SFCT, and children with faster axial growing and greater myopia increasing are usually accompanied by more SFCT thinning.

Keywords

• myopia
• subfoveal choroidal thickness
• axial length
• spherical equivalent refraction
• optical coherence tomography