Physicochemical Characterization and Prospecting Biological Activity of Some Authentic Transylvanian Essential Oils: Lavender, Sage and Basil
Dan Vârban,
Marius Zăhan,
Carmen Rodica Pop,
Sonia Socaci,
Răzvan Ștefan,
Ioana Crișan,
Loredana Elena Bota,
Ileana Miclea,
Adriana Sebastiana Muscă,
Alexandru Marius Deac,
Rodica Vârban
Affiliations
Dan Vârban
Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Marius Zăhan
Faculty of Animal Science and Biotechnology, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Carmen Rodica Pop
Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Florești No. 64, 400509 Cluj-Napoca, Romania
Sonia Socaci
Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Florești No. 64, 400509 Cluj-Napoca, Romania
Răzvan Ștefan
Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Ioana Crișan
Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Loredana Elena Bota
Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Ileana Miclea
Faculty of Animal Science and Biotechnology, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Adriana Sebastiana Muscă
Faculty of Animal Science and Biotechnology, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Alexandru Marius Deac
Faculty of Animal Science and Biotechnology, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Rodica Vârban
Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur Street No. 3–5, 400372 Cluj-Napoca, Romania
Essential oils are a category of agro-based industrial products experiencing increasing demand. In this research, three essential oils obtained by steam distillation from lavender, sage and basil plants cultivated in temperate continental conditions of Transylvania were investigated for chemical composition, physical characteristics and biological activity (antimicrobial and cytotoxic effect on cancer cell lines). The number of identified compounds varied: 38 for lavender, 29 for sage essential oil and 41 for basil. The volatile profile was dominated by terpenes and terpenoids (>80%). Major components were beta-linalool and linalool acetate in lavender essential oil; thujones and camphor in sage essential oil; beta-linalool, thujone, camphor and eucalyptol in basil essential oil. Refractive index of the essential oils was lowest for lavender and highest for sage. Antibacterial activity was strongest for basil, moderate for lavender and weakest for sage essential oil. The most active on both colon adenocarcinoma (Caco-2) and ovary carcinoma (A2780) was sage essential oil.
