Antistress property of Glycyrrhiza glabra (Athimadhura) on stress induced Drosophila melanogaster

Abstract

Stress is defined as a condition that disturbs the normal function of the biological system or a condition that decreases fitness. The present study was to evaluate the antistress property of Glycyrrhiza glabra (Athimadura). Here the Antistress property was experimented on Drosophila melanogaster. Stress was induced by adding methotrixate (MTX) to the media. The 4 groups of Drosophila melanogaster were cultured in the laboratory. In the first group only control flies. In the second group MTX induced flies, in the third group MTX along with plant powder induced flies. In the fourth group only plant powder induced flies were cultured. Stress related enzymes like Catalase (CAT) and Super Oxide Dismutase (SOD) are most widely used paradigm for the evaluation of enzyme activity . SOD and CAT Activity in Stress induced flies was increased compared to that of normal flies. After incorporation of the plant powder to the media fed for Drosophila melanogaster, both SOD and CAT Activity was decreased indicating the reduction in Stress by the plant powder. Thus Glycyrrhiza glabra may have Antistress property, as it has reduced stress in Drosophila melanogaster induced by MTX at different concentration.

Keywords

• Stress
• Drosophila
• Catalase
• Superoxide dismutase